TGT's CartiGen bioreactors impart mechanical compression to 3D samples. Applications include investigating cell function, modulating the growth and development of engineered tissues, or acting as a test bed for drug and regenerative medicine technologies. The CartiGen employs either load or displacement control to deliver user defined wave forms of physiological magnitude. Researchers are currently utilizing these systems in a wide range of research areas including:
C10-1 CartiGen Bioreactor
The C10-1 system has been designed as a single sample bioreactor system that is able to support a wide range of compression cell and tissue growth experiments via user defined stimulation protocols. This chamber can accommodate a single sample with a maximum size of 30 mm diameter x 5 mm thick. Optional features such as; transducers, non-contact micrometers, pressure sensors, etc., and/or modules to customize the instrument to specific needs can be added to accomodate the research application.
C10-12c CartiGen Bioreactor
The C10-12c system has been designed as a multi - sample bioreactor system that is able to support a wide range of compression cell and tissue growth experiments via user defined stimulation protocols. This chamber can accommodate up to 12 disc shaped samples with a maximum size of 10 mm diameter x 5 mm thick. The C10-12c's unique design includes optical grade windows on the bottom of the chamber, allowing researchers to view thier samples with a confocol microscope without interrupting the culture. Optional features such as; transducers, non-contact micrometers, pressure sensors, etc., and/or modules to customize the instrument to specific needs can be added to accomodate the research application.
Click here to download a CartiGen Brochure (Adobe PDF 16kb)
| CARTILAGE | ||
| Key: S=Standard, A=Available, - = not available | ||
| CHAMBERS | C1 | C10-12c |
| Individual sample growth chamber | S | S |
| Multi-sample growth chamber | - | S |
| Perfusion and instrumentation ports per chamber | 4 | 4 |
| Max construct size: 30 mm diameter by 5 mm thick | S | - |
| Max construct size: 10 mm diameter by 5 mm thick | S | S |
| Sample Visualization via Confocol Microscopy | - | S |
| STIMULATION | ||
| Axial stimulator and reaction frame | A | A |
| CONTROLS | ||
| Controller software, computer, and monitor | A | A |
| Power supplies and cabling | A | A |
| Mean flow control | A | A |
| Dynamic flow control | A | A |
| TISSUE MONITORING | ||
| Non-contact flow sensors | A | A |
| Catheter pressure transducers | A | A |
| ACCESSORIES | ||
| Media reservoir | S | S |
| Incubator | A | A |
| BENEFITS | ||
| All-autoclavable components | S | S |
| Medium change without operning chamber via luer fittings | S | S |
| Increased sterility with fast and clean sample change and access | S | S |
| Lightweight design for easy handling | S | S |
| Easily cleaned surface finishes | S | S |
| Compact design for fit in standard incubators | S | S |
| 100% satisfaction guaranteed warranty | S | S |
